One of the basic rules of drinking, never pass out with your shoes on. If you pass out with your shoes on, people can do whatever they want to you. Like this picture above. When you go out drinking always make sure that you eat before you go. Drinking on an empty stomach is never a good idea, you need things in your stomach be absorbed. If you go out without food in your stomach you will get drunk really quick, and nobody likes a light weight. ;)
Also, always make sure that you don't go out alone, and if you do make sure you keep your phone on you at all times. You never know what's going to happen. You need to make sure if you do go home with someone that you be responsible and make sure to use a condom.
Usually when I go out I leave one of my friends my keys so that I never have the chance to lose my room keys cause hey, lets be honest who wants to pay $50 for a new key and than $10 for an i.d card.
NEVER DRINK AND DRIVE. Which is the biggest rule of all, drinking and driving is never worth the consequences. You really don't know what could happen, and just because you didn't get caught the first time doesn't mean you'll never get caught. Drinking and driving is a really scary thing no matter what age you are. It's not that hard to call a cab, or just walk! Or even have a sober friend and take turns who drives and who drinks. It's easily avoidable, so just avoid it!!